Synthesis of 6-membered germacycles by intramolecular germylzincation of alkynes

Seydou Kassamba (1) , Mathias Reboli (1) , Alejandro Perez-Luna (2) , Franck Ferreira (2) , Muriel Durandetti (1)

1 COBRA - Chimie Organique et Bioorganique : Réactivité et Analyse
2 IPCM - Institut Parisien de Chimie Moléculaire

Intramolecular germylzincation of arylgermanes provides tetrasubstituted vinylgermanes, after post-functionalization of the vinylzinc intermediate with good regio- and stereoselectiviy.

Domaines: Chimie organique

Seydou Kassamba, Mathias Reboli, Alejandro Perez-Luna, Franck Ferreira, Muriel Durandetti. Synthesis of 6-membered germacycles by intramolecular germylzincation of alkynes. Organic Chemistry Frontiers, 2023, ⟨10.1039/D3QO00647F⟩. ⟨hal-04131064⟩